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Welcome to review links for scientific insights from multiple resources.
Study the effects of GSH (glutathione) in numerous areas as a gateway to health, including…
Cellular protection and repair*
Cell Signaling*
Exercise Tolerance*
Detoxification of Xenobiotic Compounds* and many others.
*These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease.
Regarding the Acetyl glutathione difference…
Oral Glutathione Equivalent to IV Therapy…link follows.
https://www.clinicaleducation.org/resources/reviews/oral-glutathione-equivalent-to-iv-therapy/#_ftn7
Quotation from the above linked resource…. “Acetyl Glutathione is orally active, unlike plain glutathione, and is stable in the intestine and plasma when absorbed and delivered directly to the cells for natural de-acetylation intracellularly…
…Therefore, it is a better dietary/therapeutic decision to provide the orally active and absorbed Acetyl Glutathione which increases intracellular rGSH directly and naturally without increased energy expenditure and without being compromised from disease states…
Acetyl Glutathione is more lipophilic than plain glutathione, sufficiently so to be taken up intact by cells, and has been shown to rapidly raise intracellular GSH levels…”
Glutathione dysregulation and the etiology and progression of human diseases… link follows.
“…Changes in GSH levels and/or oxidation state have now been reported in nearly all major human diseases…
…The growing recognition that GSH is involved in critical cell signaling pathways that are regulated by S-glutathionylation and/or by the thiol redox status, and that GSH may function as a neurotransmitter or neuromodulator, provides considerable new insight into possible links between GSH and disease progression…
…In addition, the recognition that GSH is intimately involved in so many disease states has generated considerable interest in identifying therapies aimed at modulating GSH levels so as to modulate disease risk or progression…”
Glutathione and Glutathione Ethyl Ester Supplementation of Mice Alter Glutathione Homeostasis during Exercise… link follows.
Study finds… “GSH treated mice swim approximately 2 hours longer and muscle lipid peroxidation is prevented.”
https://academic.oup.com/jn/article/128/12/2420/4724264
Glutathione Metabolism and Its Implications for Health… link follows.
“…GSH displays remarkable metabolic and regulatory versatility. GSH/GSSG is the most important redox couple and plays crucial roles in antioxidant defense, nutrient metabolism, and the regulation of pathways essential for whole body homeostasis. Glutathione deficiency contributes to oxidative stress, and, therefore, may play a key role in aging and the pathogenesis of many diseases…”
https://academic.oup.com/jn/article/134/3/489/4688681
Endogenous Deficiency of Glutathione as the Most Likely Cause of Serious Manifestations and Death in COVID-19 Patients… link follows.
The Role of Glutathione in Protecting against the Severe Inflammatory Response… link follows.
https://www.mdpi.com/2076-3921/9/7/624/htm
Additional resource…
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684116/